Top 10 Best-Selling DS Games of All-Time

1. Nintendogs - 22+ million sold
2. New Super Mario Bros. - 18+ million sold
3. Brain Age: Train Your Brain in Minutes a Day! - 17+ million sold
4. Pokemon Diamond and Pearl - 16+ million sold
5. Mario Kart DS - 14+ million sold
6. Brain Age 2: More Training in Minutes a Day! - 13+ million sold
7. Animal Crossing: Wild World - 10+ million sold
8. Super Mario 64 DS - 7+ million sold
9. Mario Party DS - 5+ million sold
10. Pokemon Platinum - 5+ million sold

Source: Wikipedia